Dr. Manoj Baranwal
Associate Professor

Designation:

Associate Professor

Specialization:

Immunology

Email:

manoj.baranwal@thapar.edu

Educational Qualification

  1. Ph.D (Immunology): University of Duisburg-Essen, Germany (2007)
  2. PG Diploma (Bioinformatics): Bioinformatics Centre, Jawaharlal Nehru University (JNU), New Delhi (2003)
  3. M.Sc (Life Sciences): School of Life Sciences, JNU, New Delhi (2002)
  4. B.Sc (Chemisty): Gaya College, Magadh University, Gaya (2000)

Professional Experience

  1. • Associate Professor, Dept of Biotechnology, Thapar Institute of engineering and Technology, Patiala (10th July 2017 to till date)
  2. Assistant Professor: Dept of Biotechnology, Thapar Institute of Engineering & Technology, Patiala (July 2009-July 2017)
  3. Assistant Professor: Dr. D.Y. Patil Biotechnology & Bioinformatics Institute, Pune (March 2008-July 2009)
  4. Postdoctoral Research Fellow: Institute of Immunology, University Hospital, Essen, Germany (March 2007 to January 2008)

Research Interest 

  • Immunoinformatics and cellular immunology with prime focus in peptide based vaccine design against viral disease
  • Anticancer & immunomodulatory study of natural products and nanoparticles.
  • Development of disease predictive model with application of machine learning and artificial intelligence.

Research Projects

  • In silico and in vitro approach to identify immunogenic peptides of H1N1 virus as a target for vaccine design from DST, New Delhi, Sanction amount: 23.6 Lakhs (Jan 2013 to Jan 2016) (PI)
  • Identification of T cell Epitope in H1N1 influenza virus as target for vaccine design from AICTE, New Delhi, Sanction amount: 11 lakhs (March 2012 to March 2014) (PI)
  • Immunomodulatory agents from endophytic fungi for breast cancer therapy from DBT, New Delhi, Sanction amount: 16.02 lakhs (Nov 2011 to October 2014) (PI)

As Co-Project Investigator

  • Analysis of virus transport through subsurface media from CSIR, New Delhi, Sanction amount: 23.42 lakhs (Dec 2017 to Nov 2020)

Publication of Research Articles

2018-19

  1. M. Goyal, D. Khanna, P. S. Rana, T. Khaibullin, E. Martynova, A. A. Rizvanov, S.F. Khaiboullina and M. Baranwal: Computational Intelligence Technique for Prediction of Multiple Sclerosis based on Serum Cytokines. Frontiers in Neurology, 10, 781 (2019)
  2. G. Dhiman, N. Srivastava, M. Goyal, E. Rakha, J. L. Roy, N. P. Mongan, S. F. Khaiboullina, A. Rizvanov and M. Baranwal: Metadherin: a therapeutic target in multiple cancers. Frontiers in oncology, 9, 349 (2019)
  3. S. Jain and M. Baranwal: Conserved peptide vaccine candidates containing multiple Ebola nucleoprotein epitopes display interactions with diverse HLA molecules. Medical microbiology and immunology, 208: 227-238 (2019)
  4. S. Jain and M. Baranwal: Computational analysis in designing T cell epitopes enriched peptides of Ebola glycoprotein exhibiting strong binding interaction with HLA molecules. Journal of theoretical biology, 465, 34-44 (2019)
  5. M. Goyal, H. Kaur, M. Bhandari, A. A. Rizvanov, S. F. Khaiboullina and M. Baranwal: Antioxidant and Immune Effects of Water Soluble Polysaccharides Isolated from Cinnamomum verum Bark. BioNanoScience, 8(3), 935-940 (2018)
  6. S. Khaiboullina, T. Uppal, E. Martynova, A. Rizvanov, M. Baranwal and S. C. Verma: History of ZIKV infections in India and management of disease outbreaks. Frontiers in Microbiology, 9, 2126 (2018)
  7. N. Lohia and M. Baranwal: Highly conserved hemagglutinin peptides of H1N1 influenza virus elicit immune response. 3 Biotech, 8(12), 492 (2018)
  • 2014-17
  1. N. Lohia and M. Baranwal: Immune response of highly conserved influenza A virus matrix 1 peptides. Microbiology and Immunology, 61(6), 225-231 (2017)
  2. V. Sharma, N. Lohia, V. Handa and M. Baranwal: Amomum subulatum seed extract exhibit antioxidant, cytotoxic and immune-suppressive effect (2017)
  3. M. Vasundhara, M. Baranwal, N. Sivaramaiah and A. Kumar: Isolation and characterization of trichalasin-producing endophytic fungus from Taxus baccata. Annals of Microbiology, 67(3), 255-261 (2017)
  4. G. Dhiman, N. Lohia, S. Jain and M. Baranwal: Metadherin peptides containing CD4+ and CD8+ T cell epitopes as a therapeutic vaccine candidate against cancer. Microbiology and immunology, 60(9), 646-652 (2016)
  5. P. Singh, M. Baranwal and S. M. Reddy: Antioxidant and cytotoxic activity of carotenes produced by Dunaliella salina under stress. Pharmaceutical biology, 54(10), 2269-2275 (2016)
  6. M. Vasundhara, M. Baranwal and A. Kumar: Fusarium tricinctum, an endophytic fungus exhibits cell growth inhibition and antioxidant activity. Indian journal of microbiology, 56(4), 433-438 (2016)
  7. N. Lohia and M. Baranwal: Identification of conserved peptides comprising multiple T cell epitopes of Matrix 1 protein in H1N1 influenza virus. Viral immunology, 28(10), 570-579 (2015)
  8. N. Lohia and M. Baranwal: Conserved peptides containing overlapping CD4+ and CD8+ T-cell epitopes in the H1N1 influenza virus: an immunoinformatics approach. Viral immunology, 27(5), 225-234 (2014)
  • Before 2014
  1. N. Putzki, M. K. Baranwal, B. Tettenborn, V. Limmroth and E. Kreuzfelder: Effects of natalizumab on circulating B cells, T regulatory cells and natural killer cells. European neurology, 63(5), 311-317 (2010)
  2. N. Putzki, M. Kumar, E. Kreuzfelder, H. Grosse-Wilde, H. Diener and V. Limmroth: Mitoxantrone does not restore the impaired suppressive function of natural regulatory T cells in patients suffering from multiple sclerosis. European neurology, 61(1), 27-32 (2009)
  3. Ö. Yaldizli, M. Kumar, S. Vago, E. Kreuzfelder, V. Limmroth and N. Putzki: Fatigue is not associated with impaired function of regulatory T cells in untreated patients with multiple sclerosis. European neurology, 62(6), 321 (2009)
  4. M. Kumar, N. Putzki, V. Limmroth, R. Remus, M. Lindemann, D. Knop, N. Mueller, C. Hardt, E. Kreuzfelder and H. Grosse-Wilde: CD4+ CD25+ FoxP3+ T lymphocytes fail to suppress myelin basic protein-induced proliferation in patients with multiple sclerosis. Journal of neuroimmunology, 180(1), 178-184 (2006)

Chapter

  • Tania, M. Goyal and M. Baranwal: In Silico Approach to Analyze the Biochemical Pathways of Bacterial Metabolite Synthesis. In: In Silico Approach for Sustainable Agriculture. Springer, 141-159 (2018)

Research Guidance

  • PhD: Completed (1) and Ongoing (5)
  • M.Sc/M.Tech: Completed (21)

Research Collaboration: Kazan Federal University, Russia

Membership of national/International organization

  1. Life Member of Indian Immunological society
  2. Life Member of Mycology society of India
  3. Member of German Society of Immunology from 2005-2007

Courses Taught:

Immunology, Cancer biology and infectious disease, Applied Immunology & Vaccine Technology, Advanced Bioinformatics, Bioinformatics & System Biology, Virology, Animal Biotechnology, Stem Cells, Bioethics, Environmental studies.

Programme Organized

  • 1. National conference on Emerging Trends in Biopharmaceuticals: Relevance to Human Health during, held at Thapar University, Patiala, Punjab (November 11-13th, 2010) as Organizer Secretary.
  • 2. International conference on Drug Discovery: Biotech and Pharma at CrossRoads, being organized by the Department of Biotechnology, Thapar Institute of Engineering and Technology, Patiala (15-17th Feb 2018) as Treasurer.

Reviewed Articles:

Cellular & Molecular Immunology, Pharmaceutical Biology, Cancer Biotherapy and Radiopharmaceuticals, Natural Product Research, Scientific Reports, Microbial pathogenesis, BioNanoscience, Journal of Applied phycology