Dr. Vijay Luxami
Associate Professor

  

Designation:

Associate Professor

Specialization:

Organic chemistry, Supramolecular chemistry, Molecular Recognition, Molecular Electronics, Organic materials

Email:

vluxami@thapar.edu

vjluxami@gmail.com

Contact No.

+91-9464-438-535

Education and Training:

  • 2013-2014: Visiting Scientist; Bath University, UK.
  • 2005-2010: Ph.D.; Guru Nanak Dev University, Amritsar-INDIA .
  • 2003-2005: M.Sc. Chemistry (Hons.); Guru Nanak Dev University, Amritsar-INDIA
  • 2000-2003: B.Sc. Chemistry (Hons.); Guru Nanak Dev University, Amritsar-INDIA.

Professional Affiliations

  • Associate Professor (July 2017-Present)
  • School of Chemistry and Biochemistry, Thapar Institute of Engineering & Technology, Patiala
  • Assistant Professor (June 2014 – July 2017)
  • School of Chemistry and Biochemistry, Thapar Institute of Engineering & Technology, Patiala
  • Assistant Professor-INSPIRE Faculty (August 2012 – June 2014)
  • School of Chemistry and Biochemistry, Thapar Institute of Engineering & Technology, Patiala
  • DST Young Scientist (July 2011 – July 2012)
  • School of Chemistry and Biochemistry, Thapar Institute of Engineering & Technology, Patiala-INDIA
  • Area of research: FRET based molecular probes for Metal ions
  • Lecturer (August 2010 – July 2011)
  • School of Chemistry and Biochemistry, Thapar Institute of Engineering & Technology, Patiala-INDIA

Teaching Activities

  • M.Sc. (Chemistry), SCBC, Thapar Institute of Engineering & Technology
    • PCY 302: Symmetry and Group Theory
    • PCY 211: Medicinal And Pharmaceutical Chemistry
    • PCY 308: Organic Structure Analysis
  • B.E./B.Tech., Thapar Institute of Engineering & Technology
    • UCB 008: Applied Chemistry ; Lecture, Tutorials & Practicals

List of Publications (SCI Journals)

  1. Akul Sen Gupta, Kamaldeep Paul, Vijay Luxami*, A fluorescent probe with “AIE + ESIPT” characteristics for Cu2+ and F− ions estimation, Sensors and Actuators B: Chemical, 2017, 246, 653-661.
  2. Richa Goel, Sheryl Sharma, Kamaldeep Paul, Vijay Luxami*, Naphthalimide based chromofluorescent sensor and DNA intercalator: Triggered by Hg2+/HSO4− cleavage reaction, Sensors and Actuators B: Chemical, 2017, 246, 776-782.
  3. Runjhun Tandon, Vijay Luxami, Harsovin Kaur, Nitin Tandon, and Kamaldeep Paul, 1,8-Naphthalimide: A Potent DNA Intercalator and Target for Cancer Therapy, Chem. Rec. 2017, DOI: 10.1002/tcr.201600134
  4. Prinka Singla, Vijay Luxami, Kamaldeep Paul Quinazolinone-benzimidazole conjugates: Synthesis, characterization, dihydrofolate reductase inhibition, DNA and protein binding properties, Journal of Photochem. & Photobiol., B: Biology, 2017, 168, 156-164.
  5. Akul SenGupta, Kamaldeep Paul, Vijay Luxami*, ESIPT coupled RAHB probe for estimation of cyanide in human blood serum/plasma like solution using chemodosimetric approach, Chem. Select, 2017, 2, 800-804.
  6. Prinka Singla, Vijay Luxami, Raja Singh, Vibha Tandon, Kamaldeep Paul, Novel pyrazolo[3,4-d]pyrimidine with 4-(1H-benzimidazol-2-yl)-phenylamine as broad spectrum anticancer agents: Synthesis, cell based assay, topoisomerase inhibitors, DNA intercalation and bovine serum albumin studies, Eur. J. Med. Chem. 2017, 126, 24-35.
  7. Richa Rani, Kamaldeep Paul and Vijay Luxami, An NBD-based two-in-one Cu2+/Ni2+ chemosensor with differential charge transfer processes, New J. Chem., 2016, 40, 2418.
  8. Richa Goel, Vijay Luxami and Kamaldeep Paul, Synthesis of energy transfer cassettes via click and Suzuki–Miyaura cross coupling reactions, RSC Adv., 2016, 6, 37664.
  9. Prinka Singla, Vijay Luxami and Kamaldeep Paul, Synthesis and in vitro evaluation of novel triazine analogues as anticancer agents and their interaction studies with bovine serum albumin, Eur. J. Med. Chem. 2016, 117, 59-69.
  10. Prinka Singla, Vijay Luxami, Kamaldeep Paul, Pyrrolo[2,3-b]pyridine derivatives: Synthesis and preliminary evaluation of their calf thymus DNA binding properties, Chem. Select, 2016, 1, 4772-4777.
  11. Richa Goel, Vijay Luxami and Kamaldeep Paul, Imidazo[1,2-a]pyridines: promising drug candidate for antitumor therapy, Curr. Top. Med. Chem., 2016, 16, 3590-3616.
  12. Akul Sen Gupta, Kamaldeep Paul, Vijay Luxami, Benzimidazole based ratiometric chemosensor for detection of CN- and Cu2+ ions in protic/aqueous system: Elaboration as XOR logic operation, Inorg. Chim. Acta, 2016, 443, 57–63.
  13. Richa Rani, Gulshan Kumar, Kamaldeep Paul, Vijay Luxami, Thiazolidine based differential chromo-fluorescent sensor for Cu2+ and CN- ions: Elaboration as logic devices. J. Lumin., 2016, 180, 292–300
  14. Akul Sen Gupta, Aparna Garg, Kamaldeep Paul, Vijay Luxami, Differential sensing of fluoride and cyanide ions by using Dicyano substituted benzimidazole probe, J. of Lumin., 2016, 173, 165–170.
  15. Prinka Singla, Vijay Luxami and Kamaldeep Paul, Triazine–benzimidazole conjugates: synthesis, spectroscopic and molecular modelling studies for interaction with calf thymus DNA, RSC Adv., 2016, 6, 14741.
  16. Prinka Singla, Vijay Luxami and Kamaldeep Paul, Synthesis, in vitro antitumor activity, dihydrofolate reductase inhibition, DNA intercalation and structure–activity relationship studies of 1,3,5-triazine analogues, Bioorg. & Med. Chem. Lett., 2016, 26, 518–523
  17. Alka Sharma, Vijay Luxami, Sanjai Saxena and Kamaldeep Paul, Benzimidazole-Quinazolines: In vitro Evaluation, Quantitative Structure Activity Relationship and Molecular Modeling as Aurora Kinase Inhibitors, Arch. Pharm. Chem. Life Sci. 2016, 349, 193–201.
  18. Alka Sharma, Vijay Luxami, Kamaldeep Paul, Csp2–O and C–C bond formation via Pd-catalyzed coupling reaction of 2,4-dichloroquinazoline, J. Het. Chem., 2016, 53, 241.
  19. Meenakshi Verma, Vijay Luxami and Kamaldeep Paul, Synthesis of new 2,3-disubstituted pyridines containing 1,2,3-triazole in the side-chain via one-pot copper-catalyzed azide-alkyne cycloaddition, ARKIVOC 2015 (vii) 28-41.
  20. Vijay Luxami, Richa Rani, Alka Sharma, Kamaldeep Paul, Quinazoline–benzimidazole hybrid as dual optical sensor for cyanide and Pb2+ ions and Aurora kinase inhibitor, J. of Photochem. Photobio. A: Chemistry, 2015, 311, 68-75.
  21. Akul Sen Gupta, Kamaldeep Paul, Vijay Luxami, Ratiometric fluorescent chemosensor for fluoride ion based on inhibition of excited state intramolecular proton transfer, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2015, 138, 567-72.
  22. Richa Goel, Vijay Luxami, Kamaldeep Paul, Synthetic approaches and functionalizations of imidazo[1,2-a]pyrimidines: An overview of the decade, RSC Adv., 2015, 5, 81608.
  23. Prinka Singla, Vijay Luxami, Kamaldeep Paul, Triazine as a promising scaffold for its versatile biological behavior, Eur. J. Med. Chem., 2015, 102, 39-57.
  24. Prinka Singla, Vijay Luxami, Kamaldeep Paul, Triazine–benzimidazole hybrids: Anticancer activity, DNA interaction and dihydrofolate reductase inhibitors, Bioorg. Med. Chem., 2015, 23, 1691-1700.
  25. Alka Sharma, Vijay Luxami, Kamaldeep Paul, Purine-benzimidazole hybrids: Synthesis, single crystal determination and in vitro evaluation of antitumor activities, Eur. J. Med. Chem., 2015, 93, 414-422.
  26. Meenakshi Verma, Vijay Luxami and Kamaldeep Paul, Synthesis, in vitro evaluation and DNA interaction studies of N-allyl naphthalimide analogues as anticancer agents, RSC Adv., 2015, 5, 41803-41813.
  27. Richa Goel, Vijay Luxami and Kamaldeep Paul, Synthesis, in vitro anticancer activity and SAR studies of arylated imidazo[1,2-a]pyrazine–coumarin hybrids RSC Adv., 2015, 5, 37887-37895.
  28. Richa Goel, Vijay Luxami and Kamaldeep Paul, Recent advances in development of imidazo[1,2-a]pyrazines: synthesis, reactivity and their biological applications, Org. Biomol. Chem., 2015, 13, 3525-3555. Featured on inside cover page.
  29. Navneet Kaur, Jasvinder Singh, Gargi Dhaka, Richa Rani, Vijay Luxami, Benzothiazole-based chemosensor for CN- and Cu2+: multi-logic operations within a single molecule, Supramol. Chem. 2015, 27, 453-459.
  30. Vijay Luxami, Akul Sen Gupta and Kamaldeep Paul, Dansyl-antipyrine dyad as fluorescent sensor for Cu2+ and F-: Sequential XNOR logic operation. New J. Chem., 2014, 38, 2841.
  31. Prinka Singla, Vijay Luxami and Kamaldeep Paul, Benzimidazole-Biologically Attractive Scaffold for Protein Kinase Inhibitors, RSC Adv., 2014, 4, 12422.
  32. Richa Goel, Vijay Luxami and Kamaldeep Paul, Palladium catalyzed novel monoarylation and symmetrical/unsymmetrical diarylation of imidazo[1,2-a]pyrazines and their in vitro anticancer activities, RSC Adv., 2014, 4, 9885-9892.
  33. Kamaldeep Paul, Alka Sharma, Vijay Luxami, Synthesis and in vitro antitumor evaluation of primary amine substituted quinazoline linked benzimidazole, Bioorg. Med. Chem. Lett., 2014, 24, 624-629.
  34. Meenakshi Verma, Vijay Luxami, Kamaldeep Paul, Synthesis, in vitro evaluation and molecular modelling of naphthalimide analogue as anticancer agents, Eur. J. Med. Chem. 2013, 68, 352-360.
  35. Alka Sharma, Vijay Luxami, Kamaldeep Paul, Synthesis, single crystal and antitumor activities of benzimidazole–quinazoline hybrids, Bioorg. Med. Chem.Lett., 2013, 23, 3288-3294.
  36. Kamaldeep Paul, Shweta Bindal, Vijay Luxami, Synthesis of new conjugated coumarin–benzimidazole hybrids and their anticancer activity, Bioorg. Med. Chem.Lett., 2013, 23, 3667-3672.
  37. Vijay Luxami, Renukamal, Kamaldeep Paul and Subodh Kumar, A dual-responsive chromo-fluorescent probe for detection of Zn2+ and Fe3+ via two different approaches RSC Adv., 2013, 3, 9189-9192.
  38. Vijay Luxami, Kamaldeep Paul and In Howa Jeong, Pyrophosphate selective fluorescent probe and molecular flip-flop, Dalton Trans., 2013, 42, 3783-3786.
  39. Anirudh Sharma, Atish Verma, Vijay Luxami, J. S. Melo, S. F. D’Souza, N. Tejo Prakash, and Ranjana Prakash, New Proton Nuclear Magnetic Resonance-Based Derivation for Quantification of Alkyl Esters Generated Using Biocatalysis, Energy Fuels, 2013, 27, 2660–2664.
  40. Vijay Luxami, Meenakshi Verma, Richa Rani, Kamaldeep Paul and Subodh Kumar, FRET-based ratiometric detection of Hg2+ and biothiols using naphthalimide–rhodamine dyads, Org. Biomol. Chem., 2012, 10, 8076.
  41. Vijay Luxami and Subodh Kumar ESIPT based dual fluorescent sensor and concentration dependent reconfigurable boolean operators, RSC Adv., 2012, 2, 8734-8740
  42. Vijay Luxami and Subodh Kumar, A differential ICT based molecular probe for multi-ions and multifunction logic circuits. Dalton Trans. 2012, 41, 4588
  43. Kuljit Kaur, Rajnish Saini, Ashwani Kumar, Vijay Luxami, Navneet Kaur, Prabhpreet Singh and Subodh Kumar, Chemodosimeters : An approach for estimation of biologically relevant metal ions and anions, Coord. Chem. Rev. 2012, 256, 1992.
  44. Vijay Luxami, Ashwani Kumar, Maninder Singh Hundal & Subodh Kumar, Internal electric field driven chromofluorescent chemodosimeter for fluoride ions, Sensors & Actuators:B Chem., 2010, 1.
  45. Subodh Kumar, Vijay Luxami, Rajnish Saini and Damanjit Kaur, Superimposed Molecular keypad and half-subtractor in a single fluorophore, Chem. Commun., 2009, 3044.
  46. Subodh Kumar, Vijay Luxami and Harjit Singh, Conjugates of Calixarenes and Heterocycles in Design of Newer Chemical Entities, Adv. Heterocycl. Chem. 2009, 97, 219-290.
  47. Subodh Kumar, Vijay Luxami and Ashwani Kumar, Chromofluorescent Chemosensor for fluoride and Acetate ions, Org. Lett. 2008, 10, 5549.
  48. Vijay Luxami and Subodh kumar, Molecular Half-subtractor based on 3,3`-bis-(1H-benzimidazolyl-2-yl)-[1,1`]binaphthalenyl-2,2`-diol. New J. Chem. 2008, 32, 2074. Published as Hot article.
  49. Vijay Luxami, Nidhi and Subodh Kumar, Quaternary ammonium salts based chromogenic and fluorescent chemosensors for fluoride ions Tetrahedron lett. 2008, 49, 4258.
  50. Vijay Luxami and Subodh Kumar, Colorimetric and Ratiometric Fluorescence sensing of Fluoride ions based on Competitive intra- and intermolecular proton transfer. Tetrahedron Lett. 2007, 48, 3083.
  51. Palwinder Singh, Pervinder Kaur, Vijay Luxami, Satwinderjit Kaur and Subodh Kumar, Synthesis and anti-cancer activities of 2-[1-(indol-3-yl-/pyrimidin-5-yl-/quinolin-2-yl)-but-3-enylamino]-2-phenyl-ethanols. Bioorg. & Med. Chem., 2007, 15, 2386. Article in Top 10 of Science direct.

List of Publications (Non-SCI Journals)

N/A

Book Chapters

  • Giles M. Prentice, Liam Emmett, Vijay Luxami and G. Dan Pantos, Supramolecular Chemistry of Naphthalenediimide and its Congeners, Chapter 1, Royal Society of Chemistry, 2017.
  • Subodh Kumar, Vijay Luxami and Harjit Singh, Conjugates of Calixarenes and Heterocycles in Design of Newer Chemical Entities, Adv. Heterocycl. Chem. 2009, 97, 219-290.

Awards/ Honours/ Fellowships

  • 2010: DST-DFG Award for Nobel Laureate meeting, Germany
  • 2011: SERB-DST Young Scientists’ Grant.
  • 2012: INSA-DST INSPIRE Faculty Award
  • 2012: FCT Portugese Researcher Award: Not availed
  • 2014: International travel award; Tetrahedron Symposium, Singapore.
  • 2005-2010: Junior and Senior research fellowships (JRF & SRF); Council of Scientific and Industrial Research (CSIR), New Delhi.

Sponsored Research Projects

List of ongoing projects

Year of Funding Sponsoring Agency Title of Project Grant Amount

 

(In Lacs)

Co-Investigators

 

(if any)

2012-2017 DST-INSPIRE ESIPT molecules as sensors and White Light Emitting Devices 35 Lacs ----
2016-2019 DST-Nano Mission Fabricated nano-structured organic hybrids – Chemosensors and Logic Devices 120 Prof. Subodh Kumar

List of completed projects

Year of Funding Sponsoring Organisation Title of Project Amount

 

(In Lacs)

Co-Investigators

 

(if any)

2011-2014 DST-Fast Track Heterocycles based FRET-dyads for chemionic and bioionics 27.4 ----
2012-2015 CSIR Heterocyclic substituted quinazoline and pyrazolo[3,4-d]pyrimidine derivatives: novel scaffold for Aurora Kinase inhibitors 22 Dr. Kamaldeep Paul

M.Sc. Thesis guidance

S.No. Name of Student Year of Completion Title of Thesis
1. Pranshu 2017 TPE-Fluorogens showing aiee phenomenon for sensing of Al3+ ions
2. Nehal 2017 Acrylonitrile embeded benz(imida/thia)zole based chemodosimeter for cyanide ions

 

 

3. Ravneet Kaur 2016 Pyrene based schiff bases as colorimetric and ratiometric sensors
4. Avni Reki 2016 Imidazole fused Anthraquinone derivatives as chromogenic sensors
for cations and anions
5. Aparna Garg 2015 Differential sensing of fluoride and cyanide ions by using Dicyano substituted benzimidazole probe
6. Shelly 2013 Boronic acid based molecules as saccharide sensors
7. Shweta Bindal 2012 Synthesis and In vitro evaluation of Coumarin - benzimidazole hybrids as anticancer agents
8. Maitri 2011 Benzimidazole based molecules as metal sensors and logic devices
9. Renu Kamal 2011 Rhodamine based chemosensor for selective to differential sensing of copper and iron

Ph.D. Thesis guidance

SN Name Year of Completion Title of Thesis
1. Richa Rani 2017 Fluorescent dyads as sensors for certain cations and anions
2. Akul Sen Gupta 2017 Synthesis and studies of molecules exhibiting ESIPT and AIE as sensors and logic devices
3. Gulshan Kumar Ongoing Photophysical and Theoretical studies of aza-heterocycles: Mechanistic pathways to Explore ESIPT Phenomenon
4. Ruhi Ongoing Synthesis and evaluation of Chromofluorescent properties of a new class of aza/substituted acenes
5. Richa Bansal Ongoing  
6. Aastha Ongoing  

Other Professional Activities

Served as a reviewer for international journals namely, Chem Commun, RSC Advances, JPPC, New J Chem, Sensors and Actuators, Spectrochimica Acta, etc.